Endophytic Fungi of Bitter Melon \u3ci\u3e(Momordica Charantia)\u3c/i\u3e in Guangdong Province, China

Endophytic fungi can mutualistically interact with their host plants by deterring herbivores. Overall 1172 endophytic fungal isolates were recovered from roots, stems, leaves, flowers and fruits of bitter melon, Momordica charantia, at five sites in Guangdong Province. These isolates were identified to 25 genera using morphological and molecular characteristics. The endophyte communities at the five sites were similar. Alternaria alternata, Aspergillus spp., Cladosporium spp., Colletotrichum spp., Nigrospora spp., Penicillium spp., Arthrinium spp., Chaetimium spp., Curvularia spp., Fusarium spp., Phoma spp., and Phomopsis spp. were isolated from at least three of the five sites. The coefficient of similarity for endophytes ranged from 60.6% to 83.3% between any two sites. There were significant differences in the species composition of endophytes recovered from different tissues of bitter melon. Fusarium spp. was the most frequent in root and stem samples, Colletotrichum spp. in leaf samples, A. alternata in flower samples, and Cladosporium spp. in fruit samples. The coefficients of similarity for endophytes were between 42.9% and 80.0% from any two tissues. We found that the composition of endophytes of bitter melon was relatively stable across sites, but differed greatly among tissues. We also found that there were fewer insects such as aphids (Homoptera: Aphididae), leafminers (Lepidoptera, Gracillariidae), and cotton leafworms Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) collected from the leaves of bitter melon at the Huadu site compared to those collected at the Yunfu site. Whether this is related to the endophyte communities isolated from different sites requires further research

Maximum A Posteriori Inference in Sum-Product Networks

Sum-product networks (SPNs) are a class of probabilistic graphical models that allow tractable marginal inference. However, the maximum a posteriori (MAP) inference in SPNs is NP-hard. We investigate MAP inference in SPNs from both theoretical and algorithmic perspectives. For the theoretical part, we reduce general MAP inference to its special case without evidence and hidden variables; we also show that it is NP-hard to approximate the MAP problem to $2^{n^\epsilon}$ for fixed $0 \leq \epsilon < 1$, where $n$ is the input size. For the algorithmic part, we first present an exact MAP solver that runs reasonably fast and could handle SPNs with up to 1k variables and 150k arcs in our experiments. We then present a new approximate MAP solver with a good balance between speed and accuracy, and our comprehensive experiments on real-world datasets show that it has better overall performance than existing approximate solvers

Money and Price Posting under Private Information

We study price posting with undirected search in a search-theoretic monetary model with divisible money and divisible goods. Ex ante homogeneous buyers experience match specific preference shocks in bilateral trades. The shocks follow a continuous distribution and the realization of the shocks is private information. We show that generically there exists a unique price posting monetary equilibrium. In equilibrium, each seller posts a continuous pricing schedule that exhibits quantity discounts. Buyers spend only when they have high enough preferences. As their preferences are higher, they spend more till they become cash constrained. Since inflation reduces the future purchasing power of money and the value of retaining money, buyers tend to spend their money faster in response to higher inflation. In particular, more buyers choose to spend money and buyers spend on average a higher fraction of their money. The model naturally captures the hot potato effect of inflation along both the intensive margin and the extensive margin.Economic models; Inflation and prices

A pathway analysis of genome-wide association study highlights novel type 2 diabetes risk pathways.

Genome-wide association studies (GWAS) have been widely used to identify common type 2 diabetes (T2D) variants. However, the known variants just explain less than 20% of the overall estimated genetic contribution to T2D. Pathway-based methods have been applied into T2D GWAS datasets to investigate the biological mechanisms and reported some novel T2D risk pathways. However, few pathways were shared in these studies. Here, we performed a pathway analysis using the summary results from a large-scale meta-analysis of T2D GWAS to investigate more genetic signals in T2D. Here, we selected PLNK and VEGAS to perform the gene-based test and WebGestalt to perform the pathway-based test. We identified 8 shared KEGG pathways after correction for multiple tests in both methods. We confirm previous findings, and highlight some new T2D risk pathways. We believe that our results may be helpful to study the genetic mechanisms of T2D

Integrating phytoremediation with biomass valorisation and critical element recovery: A UK contaminated land perspective

In the UK, the widespread presence of elemental contaminants such as arsenic and nickel in contaminated sites and more widely release of platinum group metals into the biosphere are growing concerns. Phytoremediation has the potential to treat land contaminated with these elements at low cost. An integrated approach combining land remediation with post-process biomass to energy conversion and high value element recovery is proposed to enhance the financial viability of phytoremediation. An analytical review of plant species suitable for the phytoremediation of nickel, Arsenic and platinum group metals is reported. Additionally, a preliminary model is developed to assess the viability of the proposed approach. A feasibility appraisal using Monte Carlo simulation to analyse project risk suggests high biomass yield plant species can significantly increase the confidence of achieving financial return from the project. The order of financial return from recovering elements was found to be: Ni > Pt > As

Subharmonic Solutions of Second Order Subquadratic Hamiltonian Systems with Potential Changing Sign

AbstractWith the aid of some symplectic transformations, the existence of subharmonic solutions of the second order Hamiltonian system −ẍ=Vx(t,x) is considered, where the potential V is subquadratic in x as |x| goes to infinity and can change sign with respect to t